KEA3: improved kinase enrichment analysis via data integration

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KEA: kinase enrichment analysis

MOTIVATION Multivariate experiments applied to mammalian cells often produce lists of proteins/genes altered under treatment versus control conditions. Such lists can be projected onto prior knowledge of kinase-substrate interactions to infer the list of kinases associated with a specific protein list. By computing how the proportion of kinases, associated with a specific list of proteins/genes...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2021

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/gkab359